SonoCoat Treated Slides

SonoCoat treated slides
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SonoPlot has developed a patented series of surface treatment processes for attaching biomolecules to a wide range of materials. These treatments are based on cold plasma exposures and vapor-phase reactions to introduce epoxide chemical groups onto the surface of a variety of materials such as glass, stainless steel, polymers, diamond and carbon nanotubes.

Our processes are a low cost and automated alternative to traditional expensive and hazardous wet-chemistry-based treatments.

Technical Specifications

FunctionalityEpoxide; covalently binds amine-containing molecules (proteins, modified oligonucleotides)
Compatible materialsOxides, polymers, novel carbon-containing materials
Compatible oxidesGlass, quartz, stainless steel, native oxide on silicon
Compatible polymersPolycarbonate, polyethylene, polypropylene, PMMA,PTFE (Teflon™), Delrin™
Compatible novel materialsCarbon nanotubes, carbon nanoparticles, diamondlike hard carbon
Biomolecule Binding DensityEquivalent to wet chemistry treatments

Technology

Cold Plasma Treatment

Cold plasmas consist of ionized gasses produced by the application of a strong electrical field. These ionized gases allow for the use of chemistries that otherwise would not be possible at room temperature. Because cold-plasma-based processes use gases and vapors instead of wet chemical baths, they have the potential to be much lower in cost, faster, more environmentally friendly, and produce a more uniform treatment.

References

F. S. Denes, S. O. Manolache, L. E. Cruz-Barba, B. J. Larson, and M. G. Lagally. Plasma-enhanced functionalization of carbon containing substrates. U.S. Patent # 7276283 (2007).
F.S. Denes, S.O. Manolache, J.M. Helgren, B.J. Larson, and M.G. Lagally. Plasma-enhanced functionalization of inorganic oxide substrates. U.S.P.T.O application # 10/809318.
B. J. Larson, J. M. Helgren, S. O. Manolache, A. Y. Lau, M. G. Lagally, and F. S. Denes Cold-plasma modification of oxide surfaces for covalent biomolecule attachment Biosensors and Bioelectronics 21, 796-801 (2005)